The Diagnostic Value of Surface Markers in Acute Appendicitis; A Diagnostic Accuracy Study

The Diagnostic Value of Surface Markers in Acute Appendicitis; A Diagnostic Accuracy Study


چاپ صفحه
پژوهان
صفحه نخست سامانه
چکیده مقاله
چکیده مقاله
نویسندگان
نویسندگان
دانلود مقاله
دانلود مقاله
علوم پزشکی اراک
علوم پزشکی اراک

نویسندگان: محمد رفیعی , قاسم مسیبی , ناصر محمدقلی مزرجی

کلمات کلیدی:

نشریه: Bulletin of Emergency and Trauma, 2,3,65 - 69,2015

اطلاعات کلی مقاله
hide/show

کد مقاله 2124
عنوان فارسی مقاله The Diagnostic Value of Surface Markers in Acute Appendicitis; A Diagnostic Accuracy Study
عنوان لاتین مقاله The Diagnostic Value of Surface Markers in Acute Appendicitis; A Diagnostic Accuracy Study
نوع مقاله بر حسب نگارش پژوهشی اصیل
مقاله برحسب نمایه PubMed.
IF 0.0
عنوان نشریه Bulletin of Emergency and Trauma
نوع نشریه علمی پژوهشی
شماره نشریه 2
دوره 3
صفحه شروع و پایان در نشریه 65 - 69
سال انتشار/ ارائه شمسی 1394
سال انتشار/ارائه میلادی 2015
آدرس لینک مقاله/ همایش در شبکه اینترنت http://www.ncbi.nlm.nih.gov/pubmed/?term=The+Diagnostic+Value+of+Surface+Markers+in+Acute+Appendicitis%3B+A+Diagnostic+Accuracy+
ISSN 2322-2522
DOI
آدرس علمی (Affiliation) نویسنده متقاضی Department of Biostatistics, School of Medicine, Arak University of Medical Sciences, Arak, Iran

چکیده مقاله
hide/show

عنوان متن
چکیده انگلیسیThe Diagnostic Value of Surface Markers in Acute Appendicitis; A Diagnostic Accuracy Study Gholi Mezerji NM1, Rafeie M1, Shayan Z2, Mosayebi G3. • 1Department of Biostatistics, School of Medicine, Arak University of Medical Sciences, Arak, Iran. • 2Trauma Research Center, Department of Community Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. • 3Department of Immunology and Microbiology, School of Medicine, Arak University of Medical Sciences, Arak, Iran. Abstract OBJECTIVE: To determine the diagnostic value of blood cells surface markers in patients with acute appendicitis. METHODS: In this cross-sectional study, 71 patients who underwent appendectomy following a diagnosis of appendicitis were recruited during a one-year period. The patients were divided into two groups: patients with histopathologically confirmed acute appendicitis and subjects with normal appendix. Blood cell surface markers of all patients were measured. Univariate and multivariate analytical methods were applied to identify the most useful markers. Receiver operating characteristics (ROC) curves were also used to find the best cut-off point, sensitivity, and specificity. RESULTS: Overall we included 71 patients with mean age of 22.6±10.7 years. Of the 71 cases, 45 (63.4%) had acute appendicitis while 26 (36.6%) were normal. There was no significant difference between two study groups regarding the age (p=0.151) and sex (p=0.142). The initial WBC count was significantly higher in those with acute appendicitis (p=0.033). Maximum and minimum area under the ROC curve in univariate analysis was reported for CD3/RA (0.71) and CD38 (0.533), respectively. Multivariate regression models revealed the percentage of accurate diagnoses based on the combination of γ/δ TCR, CD3/RO, and CD3/RA markers to be 74.65%. Maximum area under the ROC curve (0.79) was also obtained for the same combination. CONCLUSION: the best blood cell surface markers in the prediction of acute appendicitis were HLA-DR+CD19, a/β TCR, and CD3/RA. The simultaneous use of γ/δ TCR, CD3/RA, and CD3/RO showed the highest diagnostic value in acute appendicitis. KEYWORDS: Acute appendicitis; Blood cell surface markers; Diagnostic accuracy; ROC curve
چکیده
کلمات کلیدی
نام فایل عنوان پیوست تاریخ درج فایل اندازه فایل دانلود
2124.pdfچکیده لاتین1395/03/1558532دانلود

نویسندگان
hide/show

نویسنده نفر چندم مقاله
محمد رفیعیدوم
قاسم مسیبیچهارم
ناصر محمدقلی مزرجیاول

لینک دانلود مقاله
hide/show

نام فایل عنوان پیوست تاریخ درج فایل اندازه فایل دانلود
2124.pdfمتن کامل مقاله1395/03/17755938دانلود