Assessment of immune status in relation to vitamin D levels in patients with severe sepsis.

Assessment of immune status in relation to vitamin D levels in patients with severe sepsis.


چاپ صفحه
پژوهان
صفحه نخست سامانه
چکیده مقاله
چکیده مقاله
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علوم پزشکی اراک
علوم پزشکی اراک

نویسندگان: قاسم مسیبی , ابوالفضل جوکار , قاسم مشار موحد

کلمات کلیدی: Keywords: Vitamin D levels, Immune status, Sepsis, Patient, Serum.

نشریه: Biomedical Research, 20,,8655 - 8559,2017

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کد مقاله 4181
عنوان فارسی مقاله Assessment of immune status in relation to vitamin D levels in patients with severe sepsis.
عنوان لاتین مقاله Assessment of immune status in relation to vitamin D levels in patients with severe sepsis.
نوع مقاله بر حسب نگارش پژوهشی اصیل
مقاله برحسب نمایه scopus
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عنوان نشریه Biomedical Research
نوع نشریه علمی پژوهشی
شماره نشریه 20
دوره 28
صفحه شروع و پایان در نشریه 8655 - 8559
سال انتشار/ ارائه شمسی 1396
سال انتشار/ارائه میلادی 2017
آدرس لینک مقاله/ همایش در شبکه اینترنت --
ISSN 0970-938x
DOI
آدرس علمی (Affiliation) نویسنده متقاضی Department of Emergency Medicine, Arak University of Medical Sciences, Arak, Iran

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عنوان متن
چکیده انگلیسیIntroduction: Systemic sepsis is the body's response to invading microorganisms is from bacteria and fungi. In the most severely ill patients are vitamin D deficient. Since vitamin D in innate and adaptive immune responses is essential for the proper functioning of antimicrobials. The aim of this clinical trial to evaluate the safety associated with vitamin D levels in patients with severe sepsis. Methods: In this clinical trial, 60 patients with sepsis were divided into 3 groups of 20 and 20 cases of healthy people as a control group was considered. Serum levels of IL-10 and TNF-alpha, length of stay and mortality were recorded. The data was analysed. Results: A statistically significant difference in mean age and sex distribution between the groups was observed. The patients showed a significant difference that indicates that vitamin D deficiency in the number of people admitted they were more than the other two groups were fatal. The mean levels of vitamin D, IL-10 and TNF levels in vitamin D deficiency showed significant differences between groups (P value=001/0). Conclusion: The results and lack of complication in the use of vitamin D muscle, as well as ease of use and low cost of these medications can these drugs in improving patient safety sepsis and reduce hospital admissions and deaths and morbidity can be as adjunctive therapy in the treatment of patients with symptoms of sepsis can be used.
چکیده
کلمات کلیدیKeywords: Vitamin D levels, Immune status, Sepsis, Patient, Serum.
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نویسنده نفر چندم مقاله
قاسم مسیبیدوم
ابوالفضل جوکاراول
قاسم مشار موحدسوم

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