Bone marrow‐mesenchymal stem cells impact on the U937 cells in the presence of staphylococcal enterotoxin B (SEB)

Bone marrow‐mesenchymal stem cells impact on the U937 cells in the presence of staphylococcal enterotoxin B (SEB)


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نویسندگان: علی قضاوی , قاسم مسیبی , بهزاد خوانساری نژاد

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نشریه: Clinical and Experimental Pharmacology and Physiology, 8,,849 - 858,2018

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کد مقاله 4438
عنوان فارسی مقاله Bone marrow‐mesenchymal stem cells impact on the U937 cells in the presence of staphylococcal enterotoxin B (SEB)
عنوان لاتین مقاله Bone marrow‐mesenchymal stem cells impact on the U937 cells in the presence of staphylococcal enterotoxin B (SEB)
نوع مقاله بر حسب نگارش پژوهشی اصیل
مقاله برحسب نمایه ISI
IF 2.1
عنوان نشریه Clinical and Experimental Pharmacology and Physiology
نوع نشریه علمی پژوهشی
شماره نشریه 8
دوره 45
صفحه شروع و پایان در نشریه 849 - 858
سال انتشار/ ارائه شمسی 1397
سال انتشار/ارائه میلادی 2018
آدرس لینک مقاله/ همایش در شبکه اینترنت
ISSN 1440-1681
DOI DOI: 10.1155/2018/1423939
آدرس علمی (Affiliation) نویسنده متقاضی 1Molecular and Medicine Research Center (MMRC), Department of Microbiology and Immunology,

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چکیده انگلیسیAbstract OBJECTIVES: Incidence of methicillin-resistant Staphylococcus aureus (MRSA) is increasing every year, especially in burn patients with a high rate of morbidity and mortality. Molecular and epidemiologic studies are useful practices for understanding the relatedness of isolates in a single patient or a hospital. This study aimed at determining molecular characterizations of isolates collected in 2006 and 2014 using S. aureus-specific staphylococcal protein A (Spa) typing and Multilocus Sequence Typing (MLST) methods. MATERIALS AND METHODS: Totally, 71 MRSA isolates were collected during the last two studies (2006 and 2014) from burn patients at Taleghani Burn Centre. After confirmation, all isolates were analysed using MLST and Spa typing methods. RESULTS: We reported the emergence of Spa type t021, ST-30-IV MRSA isolates, which were PVL-positive in 14.6% of the cases and t12366, ST-8-IV isolates, which were PVL-negative in 9.8% of the cases. In 2014 study, Spa typing of MRSA isolates revealed five different spa types. Overall, in two studies, t037, ST-239, SCCmec III, and CC8 were predominant clones and they were reported in 63% of the cases. CONCLUSION: The predominance of ST-239 in this region during the last eight years is a major concern. It also has a disturbing impact on the management of staphylococcal infections. Moreover, the SCCmec type IV strain is able to disseminate rapidly in hospital environments, demanding an improvement in infection-control policy
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نویسنده نفر چندم مقاله
علی قضاویسوم
قاسم مسیبیپنجم و مسئول
بهزاد خوانساری نژادچهارم

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Bone marrow - mesenchymal stem cells impact on the U937 cells in the presence of staphylococcal enterotoxin B (SEB).pdfاصل مقاله1397/05/064694016دانلود
Impact factor CEPP.pdfImpact factor1397/05/06365327دانلود
JCR CEPP.pdf 1397/05/06232548دانلود